Supplements: Should I take the colon cleanser, prebiotic, and probioti Skip to content.

Should I take the colon cleanser, prebiotic, and probiotic together?

Typically, we suggest first taking the colon cleanser for a few days and then to start the prebiotic and probiotic a few days later. You can take the prebiotic and probiotic together, and with or without food. And the time of day that you take them is a personal preference!